MCQ 51 All the following familial syndromes are associated with development of pheochromocytomas except:


 A.Sturge-Weber syndrome
B.Von Recklinghausen disease
C.MEN type II
D.Prader-Willi syndrome



The correct answer is :  D.Prader-Willi syndrome

NOTE: Pheochromocytoma is a catecholamine (usually noradrenaline and adrenaline in lesser extent) secreting tumor which is derived from chromaffin cells of adrenal glands or extradrenal chromaffin tissue.It is rare but dangerous because excessive amounts catecholamines may precipitate life threatening hypertension or cardiac arrythmias.

Pheochromocytomo is associated with the following familial syndromes:
  • MEN syndromes type II and type III
  • Von Hippel Lindau syndrome
  • Von Recklinghausen disease
  • Sturge weber syndrome
Nested arrangement of cells (Zellballen) and stippled chromatin

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